Table 1. Binding partners of LIM‐domain‐binding protein 1
ProteinFunctionReference
Binds to the Ldb1 dimerization domain (DD)
PannierProneural development and thorax patterningRamain et al., 2000
OsaRepression of proneural developmentHeitzler et al., 2003
RLIMCofactor exchange, neuronal developmentOstendorff et al., 2002
Binds to the Ldb1 LIM interaction domain (LID)
LIM‐HD (for example, Isl, Lhx, Lmx)Cell specification and developmentReviewed in Bach, 2000; Hobert & Westphal, 2000
LMOCell proliferationReviewed in Bach, 2000
ASC–Da heterodimerProneural development, thorax patterningRamain et al., 2000
Binds to the other interaction domain (OID)
SuHw, Modifier of Mdg4Enhancer–promoter communicationGause et al., 2001; Torigoi et al., 2000
Bcd, FtzSegmentation in DrosophilaTorigoi et al., 2000
ChipHomodimerizationTorigoi et al., 2000
Binds to Ldb1/Chip conserved domain (LLCD)
SsdpAxis induction, wing developmentChen et al., 2002; Van Meyel et al., 2003
Undefined binding site on Ldb1
LIN‐11Vulval morphogenesisGupta et al., 2003
  • ASC, Achaete–Scute complex; Bcd, Bicoid; Da, Daughterless; Ftz, Fushi tarazu; HD, homeodomain; LMO, LIM‐only protein; Ssdb, single‐stranded DNA‐binding proteins; SuHw, Suppressor of Hairy wing.