Table 1. S. cerevisiae gene families showing ectopic recombination
Family descriptionSequences in S288cTotal number of sequences retreivedSubtelomericCell‐surface
Genes coding for (putative) Helicase‐like proteins31323YesNo
HXT family16213YesYes
COS family9116YesYes
Genes coding for (Iso)maltases786YesNo
AAD gene family774YesNo
FLO gene family619YesYes
Type I transmembrane sorting receptor for vacuolar hydrolases and similar sequences669YesNo
PHO gene family579YesYes
Pheromone‐regulated protein with a motif involved in COPII binding/putative integral membrane protein427NoYes
Genes coding for MAL activators475YesNo
ENA gene family319NoYes
TDH gene family352NoNo
FRE gene family355NoYes
Transporters of thiamine/nicotinamide riboside344NoYes
TPO gene family224NoYes
  • FLO, flocculation.

  • Examples of some representative S. cerevisiae gene families that undergo ectopic recombination (for a full list, see supplementary Dataset S1 online). The table contains 15 gene families that contain at least one chimaeric sequence (PHI value<10−16). First column lists function of characterized members of the identified gene family, ‘sequences in S288c’ lists the number of members of each gene family present in the S288c reference genome, whereas ‘sequences retrieved’ lists represents the total number of sequences found in 24 genomes (supplementary Table S1 online). Gene families are classified as subtelomeric or cell‐surface if at least two sequences in the family meet the characteristic.