Table of Contents

Articles

• Open Access

  Brd4‐Brd2 isoform switching coordinates pluripotent exit and Smad2‐dependent lineage specification

  

  Rosalia Fernandez‐Alonso, Lindsay Davidson, Jens Hukelmann, Michael Zengerle, Alan R Prescott, Angus Lamond, Alessio Ciulli, Gopal P Sapkota, Greg M Findlay

  Published online 06.06.2017

  • Signal Transduction
  • Stem Cells
• Open Access

  Mfn2 deletion in brown adipose tissue protects from insulin resistance and impairs thermogenesis

  

  Kiana Mahdaviani, Ilan Y Benador, Shi Su, Raffi A Gharakhanian, Linsey Stiles, Kyle M Trudeau, Maria Cardamone, Violeta Enríquez‐Zarralanga, Eleni Ritou, Tamar Aprahamian, Marcus F Oliveira, Barbara E Corkey, Valentina Perissi, Marc Liesa, Orian S Shirihai

  Published online 24.05.2017

  • Membrane & Intracellular Transport
  • Metabolism
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  Bacilli glutamate dehydrogenases diverged via coevolution of transcription and enzyme regulation

  

  Lianet Noda‐Garcia, Maria Luisa Romero Romero, Liam M Longo, Ilana Kolodkin‐Gal, Dan S Tawfik

  Published online 03.05.2017

  • Evolution
  • Metabolism
  • Microbiology, Virology & Host Pathogen Interaction
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  Lipophagy prevents activity‐dependent neurodegeneration due to dihydroceramide accumulation in vivo

  

  Wei‐Hung Jung, Chung‐Chih Liu, Yu‐Lian Yu, Yu‐Chin Chang, Wen‐Yu Lien, Hsi‐Chun Chao, Shu‐Yi Huang, Ching‐Hua Kuo, Han‐Chen Ho, Chih‐Chiang Chan

  Published online 15.05.2017

  • Autophagy & Cell Death
  • Metabolism
  • Neuroscience
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  Salt‐inducible kinase induces cytoplasmic histone deacetylase 4 to promote vascular calcification

  

  Alon Abend, Omer Shkedi, Michal Fertouk, Lilac H Caspi, Izhak Kehat

  Published online 06.06.2017

  • Chromatin, Epigenetics, Genomics & Functional Genomics
  • Molecular Biology of Disease
  • Post-translational Modifications, Proteolysis & Proteomics
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  TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury

  

  Fargol Mazaheri, Nicolas Snaidero, Gernot Kleinberger, Charlotte Madore, Anna Daria, Georg Werner, Susanne Krasemann, Anja Capell, Dietrich Trümbach, Wolfgang Wurst, Bettina Brunner, Sebastian Bultmann, Sabina Tahirovic, Martin Kerschensteiner, Thomas Misgeld, Oleg Butovsky, Christian Haass

  Published online 08.05.2017

  • Immunology
  • Molecular Biology of Disease
  • Neuroscience
• Open Access

  Circadian networks in human embryonic stem cell‐derived cardiomyocytes

  

  Pieterjan Dierickx, Marit W Vermunt, Mauro J Muraro, Menno P Creyghton, Pieter A Doevendans, Alexander van Oudenaarden, Niels Geijsen, Linda W Van Laake

  Published online 23.05.2017

  • Development & Differentiation
  • Stem Cells
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  Synergistic action of auxin and cytokinin mediates aluminum‐induced root growth inhibition in Arabidopsis

  

  Zhong‐Bao Yang, Guangchao Liu, Jiajia Liu, Bing Zhang, Wenjing Meng, Bruno Müller, Ken‐ichiro Hayashi, Xiansheng Zhang, Zhong Zhao, Ive De Smet, Zhaojun Ding

  Published online 09.06.2017

  • Plant Biology
  • Signal Transduction
• Open Access

  Transposon‐driven transcription is a conserved feature of vertebrate spermatogenesis and transcript evolution

  

  Matthew P Davis, Claudia Carrieri, Harpreet K Saini, Stijn van Dongen, Tommaso Leonardi, Giovanni Bussotti, Jack M Monahan, Tania Auchynnikava, Angelo Bitetti, Juri Rappsilber, Robin C Allshire, Alena Shkumatava, Dónal O'Carroll, Anton J Enright

  Published online 12.05.2017

  • Chromatin, Epigenetics, Genomics & Functional Genomics
  • Transcription
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  The RNA helicase DHX9 establishes nucleolar heterochromatin, and this activity is required for embryonic stem cell differentiation

  

  Sergio Leone, Dominik Bär, Coenraad Frederik Slabber, Damian Dalcher, Raffaella Santoro

  Published online 06.06.2017

  • Chromatin, Epigenetics, Genomics & Functional Genomics
  • RNA Biology
  • Stem Cells